Cardiovascular (CV)

Cardiovascular (CV)

Cardiovascular disease from renin angiotensin aldosterone system (RAAS) dysfunction arises when overactivation of the pathway drives excess angiotensin II production, leading to vasoconstriction, sodium retention, vascular remodelling, and hypertension. The consequences of uncontrolled hypertension are associated with significant physical and psychosocial impacts on patients' daily lives.

Resources

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Renin-Angiotensin System (RAS) In Hypertension Video
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Congresses

International Porphyrias Symposium (IPS) 2025 Congress, USA

Cardiovascular (CV)

American Heart Association (AHA) 2025

European Society of Cardiology (ESC) 2025 CV Congress, Spain

Cardiovascular (CV)

European Society of Cardiology (ESC) 2025

American Heart Association (AHA) 2024 CV Congress, USA

Cardiovascular (CV)

American Heart Association (AHA) 2024

Publications

Cardiovascular (CV)

Add-on Treatment With Zilebesiran for Inadequately Controlled Hypertension: The KARDIA-2 Randomised Clinical Trial

JAMA

Author(s)

Akshay S. Desai, Adam D. Karns, Jolita Badariene

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