Cardiovascular (CV)
Cardiovascular disease from renin angiotensin aldosterone system (RAAS) dysfunction arises when overactivation of the pathway drives excess angiotensin II production, leading to vasoconstriction, sodium retention, vascular remodelling, and hypertension. The consequences of uncontrolled hypertension are associated with significant physical and psychosocial impacts on patients' daily lives.
Resources
Congresses
Cardiovascular (CV)
American Heart Association (AHA) 2025
Cardiovascular (CV)
European Society of Cardiology (ESC) 2025
Cardiovascular (CV)
American Heart Association (AHA) 2024
Publications
Cardiovascular (CV)
Add-on Treatment With Zilebesiran for Inadequately Controlled Hypertension: The KARDIA-2 Randomised Clinical Trial
JAMA
